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CBSE Class 12 Biology 2022 question paper (57/2)

Maximum marks 35 · Time 2 hours · 3 sets

Try each question first, then open its model answer. Where the paper offers a choice, both questions are shown with OR between them.

Section A

2 marks each

  1. Q.12 marks
    Though filariasis is not fatal, but the disease in humans is responsible for considerable suffering, gross deformities and disability. Write the scientific name of any two helminth worms causing the disease and state two chronic manifestations of filariasis.
  2. Q.22 marks
    "Curd is easier to digest by humans than milk." Justify, giving two suitable reasons.
  3. Q.3 (a)2 marks
    A person suffering from AIDS dies of opportunistic infections (ARC) i.e., infections that could have been otherwise overcome. (i) State one reason as to why an 'HIV' patient dies of 'opportunistic infections'. (ii) Give the scientific name of one bacterium and one parasite which mainly attack a person suffering from AIDS. (iii) Write the full form of the name of the widely used diagnostic test for AIDS.
  4. OR

    Q.3 (b)2 marks
    In spite of the statutory warning on cigarette packets against 'smoking' and its injurious effects on health, smoking is still prevalent in the society. Enumerate four important health hazards to a smoker.
  5. Q.42 marks
    Study the given diagrams of Biogas plants – 'A' and 'B' and answer the questions that follow : Which one of the two biogas plants can be used for generating gas fuel and electricity and why ? Give suitable reasons in support of your answer.
  6. Q.52 marks
    Explain the two physiological attributes which enable a kangaroo rat to survive in desert conditions.
  7. Q.6 (a)2 marks
    Study the given graphs (X) and (Y) depicting the annual variation in solar radiation on Earth from January to December and answer the undermentioned questions. (i) Identify the graph that depicts (I) tropical region, and (II) temperate region, respectively. (ii) Which of the two regions, (X) or (Y), will show high biological diversity and why ? Give two reasons.
  8. OR

    Q.6 (b)2 marks
    (i) When prickly pear cactus was introduced into Australia in early 1920s, it caused havoc and ecosystem instability by achieving very high population densities. Explain the reason for its rapid spread into millions of hectares of rangeland. (ii) State the importance of 'Prey-predator' relationship in a habitat.

Section B

3 marks each

  1. Q.73 marks
    When Plasmodium sp. (malarial parasite) enters the human body, it reproduces asexually and increases its number. During this course, the affected person suffers from malaria. After a number of asexual cycles, the parasite, in order to complete its life cycle, enters the sexual phase of its life. Trace the sexual stages in the life cycle of Plasmodium in a female Anopheles mosquito, when it bites an infected person, up to the formation of mature infective stages of the parasite.
  2. Q.83 marks
    (a) Name and state the type of immunity that acts as a 'biological shield' to the developing foetus against many infections in the mother's womb. (b) A large proportion of infants remain free from potent infections at least three months after birth, or even longer if breast fed. Explain, giving suitable reasons.
  3. Q.93 marks
    With the advent of sophisticated techniques of genetic engineering, we can now readily purify and isolate DNA. Name and explain the different steps involved in the separation and isolation of DNA fragments once cut by restriction endonucleases.
  4. Q.10 (a)3 marks
    "Some species in an ecosystem exert greater influence in driving major ecosystem services than others." How did Paul Ehrlich explain this concept in his 'rivet popper hypothesis' ?
  5. OR

    Q.10 (b)3 marks
    (i) How has the introduction of Nile Perch into Lake Victoria in East Africa had a devastating effect on the indigenous species in the lake ? (ii) Name two invasive weed species which have posed a threat to the existence of our native species.
  6. Q.113 marks
    Given below is a picture of a natural large habitat that is being continuously broken into smaller patches. This process is continuing, increasing and expanding over time due to human impact, thereby posing a great risk to the existence of species in the habitat. (a) Do you agree with the above statement ? Give two suitable reasons in support of your answer. (b) Write the ecological term used for such patches formed in an original habitat.
  7. Q.123 marks
    An application of biotechnology in agriculture involves production of pest resistant plants using 'cry' genes from a bacterium. Name the bacterium. Explain why the 'cry' gene kills the pest but not the bacterium itself.

Section C

1 mark each

  1. Development of recombinant DNA technology has opened gates to many breakthroughs in the fields of medicine and agriculture. This has enabled scientists to isolate, sequence and manipulate individual genes obtained from diverse living or dead cells. Given below is a diagram showing the basic steps involved in genetically modifying an organism. Study the given diagram and answer the questions that follow :
    Q.13 (a) (i)1 mark
    Are two different types of restriction endonucleases used, one to cut the vector DNA and another to cut the desired DNA to be cloned ? Support your answer, giving reason.
  2. Q.13 (a) (ii)1 mark
    Which enzyme is used at step (X) to integrate the foreign DNA with the vector DNA ?
  3. Q.13 (a) (iii)1 mark
    What is the term used for step (Y) showing multiple copies of the foreign DNA being formed in transformed E. coli ?
  4. Q.13 (a) (iv)1 mark
    Draw a diagram of E. coli cloning vector pBR322 to show the following : (I) Any one restriction endonuclease site in tetracycline resistance gene (II) Any one restriction endonuclease site in ampicillin resistance gene (III) 'ori' site
  5. Q.13 (a) (v)1 mark
    What does "rop" code for in plasmid pBR322 ?
  6. OR

    RNA interference (RNAi) holds great potential as a therapeutic agent for the treatment of human diseases and as a bicontrol agent for controlling pests in the agricultural fields. An experiment was conducted to study the use of 'RNAi' for the potential treatment of disorders of cholesterol metabolism. Some people possess genetic mutations with elevated levels of 'ApoB' gene which predisposes them to coronary artery diseases. Lowering the amount of 'ApoB' can reduce the number of lipoproteins and lower the blood cholesterol. Tracy Zimmerman and her colleagues used RNAi in 2006 to reduce the level of 'ApoB' in non-human primates Cynomolgus monkeys. (i) One group of monkeys were given RNAi treatment (Small interfering RNAs, SiRNAs) (doses 1 mg/kg SiRNAs), (ii) Second group of monkeys were given RNAi treatment (doses 2⋅52{\cdot}5 mg/kg SiRNAs), and (iii) Third group of monkeys were injected saline as control . The results of the experiments are illustrated in the graph given below :
    Q.13 (b)5 marks
    (i) What do you interpret from the bars (X and Z) obtained after 264 hours of treatment of monkeys with saline and 2⋅52{\cdot}5 mg/kg SiRNAs treatment ? (ii) Name the category of organisms in the living world, where RNA interference (RNAi) takes place. Why ? (iii) What is the basic principle involved in RNA interference (RNAi) in silencing the preferred genes ?