PYQ Vault

CBSE Class 12 Biology 2026 question paper (57/3)

Maximum marks 70 · Time 3 hours · 3 sets

Try each question first, then open its model answer. Where the paper offers a choice, both questions are shown with OR between them.

Section A

1 mark each

  1. Q.11 mark
    Foetal ejection reflex in human female triggers the release of which hormone ?

    Tap an option to check your answer.

  2. Q.21 mark
    Which of the following is not a functional unit of an ecosystem ?

    Tap an option to check your answer.

  3. Q.31 mark
    Match Column I with Column II and select the correct option :
    Column IColumn II
    a. Primersi. β\beta-galactosidase
    b. Insertional inactivationii. To separate and purify products
    c. Bioreactoriii. Chemically synthesized oligonucleotides
    d. Downstream processingiv. Large scale production of specific product of activity of microbes

    Tap an option to check your answer.

  4. Q.41 mark
    Golden rice is a promising transgenic crop. When released for cultivation, it will help in :

    Tap an option to check your answer.

  5. Q.51 mark
    Four different transcription units are shown below. Choose the option with the correct image.

    Tap an option to check your answer.

  6. Q.61 mark
    Appearance of antibiotic-resistant bacteria is an example of evolution due to :

    Tap an option to check your answer.

  7. Q.71 mark
    Identify the statements that correctly describe Darwin's Theory of Evolution. (i) Overproduction of organisms leads to competition. (ii) Variation is inherited and causes evolution. (iii) Acquired characters are inherited. (iv) Survival depends on favourable traits. (v) New species arise due to accumulation of favourable variations. Choose the correct option.

    Tap an option to check your answer.

  8. Q.81 mark
    Which of the following is not a symptom of Ascariasis ?

    Tap an option to check your answer.

  9. Q.91 mark
    Every trophic level has a certain mass of living material at a particular time. What is it called ?

    Tap an option to check your answer.

  10. Q.101 mark
    The smallest part of DNA molecule that can be changed by point mutation is :

    Tap an option to check your answer.

  11. Q.111 mark
    Some statements regarding drugs and alcohol are given below : (i) Adolescents are more vulnerable to peer pressure. (ii) Drug addiction leads to increased tolerance level of the receptors present in our body. (iii) Alcohol affects the central nervous system. (iv) Excessive use of drugs helps to increase energy. (v) Anabolic steroids decrease aggressiveness. Choose the option with correct statement(s).

    Tap an option to check your answer.

  12. Q.121 mark
    Select the correct option for the pair of plants pollinated by water.

    Tap an option to check your answer.

  13. For Questions number 13 to 16, two statements are given – one labelled as Assertion (A) and the other labelled as Reason (R). Select the correct answer to these questions from the codes (A), (B), (C) and (D) as given below.
    Q.131 mark
    Assertion (A) : Activated sludge contains large population of bacteria. Reason (R) : These bacteria help in anaerobic digestion of human waste in biogas plant.

    Tap an option to check your answer.

  14. Q.141 mark
    Assertion (A) : Ecosystems require a constant supply of energy to synthesize the molecules they require. Reason (R) : This is to counteract the universal tendency towards increasing disorderliness as per Second Law of Thermodynamics.

    Tap an option to check your answer.

  15. Q.151 mark
    Assertion (A) : DNA cannot pass through cell membrane of a bacterial cell. Reason (R) : DNA is a hydrophilic molecule.

    Tap an option to check your answer.

  16. Q.161 mark
    Assertion (A) : Repetitive sequences are stretches of DNA sequences that are thought to have no direct coding functions. Reason (R) : They shed light on chromosome structure, dynamics and evolution.

    Tap an option to check your answer.

Section B

2 marks each

  1. Q.17 (a)2 marks
    A person complains of persistent itching in the groin region and scalp. The person also shows dry and scaly lesions on skin, nails, etc. (i) Identify the disease. (ii) Name its two causative agents. (iii) Mention its mode of transmission.
  2. OR

    Q.17 (b)2 marks
    A girl develops sneezing, watery eyes and difficulty in breathing every time she visits a flower garden. (i) Identify the condition. (ii) Name the immune component responsible for this condition. (iii) Name the chemical released. (iv) State one medicine used to treat such a condition.
  3. Q.18 (a)2 marks
    (i) Mention any two characteristics of Neanderthal man that lived near East and Central Asia. (ii) Identify the following hominids with respect to human evolution : (I) Brain capacity 900 cc, probably ate meat. (II) First human-like with brain capacity 650 – 800 cc.
  4. OR

    Q.18 (b)2 marks
    The allele for brown eyes (B) is dominant over blue eyes (b). In a population, 36% of individuals have blue eyes. Assuming Hardy-Weinberg equilibrium, calculate : (i) Frequency of allele B (ii) Percentage of heterozygous individuals (iii) Percentage of individuals that are homozygous dominant (Working to be shown)
  5. Q.192 marks
    What did Henking observe in his experiments on insects that led to the discovery of sex chromosome ? How did his observation contribute to our understanding of sex determination ?
  6. Q.20 (a)2 marks
    (i) Given below is the schematic representation of the process of electrophoresis. Identify the alphabets representing the : (I) Anode end, and (II) Lightest/Smallest DNA in matrix. (ii) What is Agarose gel and why is it used in this process ?
  7. OR

    Q.20 (b)2 marks
    After performing gel electrophoresis, a student observes that DNA fragments are not visible. (i) Suggest a reason for this and explain how fragments can be made visible. (ii) Also explain how a specific DNA fragment can be collected from the gel for further use.
  8. Q.212 marks
    GEAC is a regulatory body under the Ministry of Environment, Forest and Climate Change in India. (a) Write the full form of GEAC. (b) Mention two of its important functions related to biotechnology.

Section C

3 marks each

  1. Q.223 marks
    Answer the following questions : (a) Explain the different ways by which apomictic seeds can be developed. (b) Mention one advantage of apomictic seeds for farmers.
  2. Q.233 marks
    (a) What is meant by translation in protein synthesis ? (b) Explain charging of tRNA (aminoacylation of tRNA) and mention its importance in the process of translation.
  3. Q.243 marks
    (a) What is the carrying capacity of a species in a habitat ? (b) Explain the growth curve that takes this capacity into account.
  4. Q.253 marks
    In vitro fertilization (IVF) is a popular method these days that is helping childless couples to bear a child. (a) Write the different steps that are carried out in this technique. (b) Would you consider gamete intra fallopian transfer as a type of IVF ? Justify your answer.
  5. Q.263 marks
    Draw a neat diagram of a maize grain showing the internal structure and label any five parts.
  6. Q.273 marks
    Cow dung and water are mixed and fed into a biogas plant to allow digestion of biowastes. The person performing this process says that there is no need to provide an inoculum. (a) Do you agree with him ? Justify your answer. (b) What happens to the biowaste inside the digester ? (c) Name the useful by-products obtained from this process and mention how they are used.
  7. Q.283 marks
    (a) Describe the experiment conducted by T.H. Morgan on Drosophila melanogaster involving eye colour and body colour. (b) How did the results deviate from Mendelian inheritance pattern ? (c) Explain the two genetic terms used by Morgan for his observations.

Section D

  1. The data below shows the concentration of nicotine smoked by a smoker taking 10 puffs/minute.
    Q.29 (a) (i)1 mark
    With reference to the above graph, explain the concentration of nicotine in the blood at 10 minutes.
  2. OR

    Q.29 (a) (ii)1 mark
    How will this affect the concentration of carbon monoxide and haem-bound oxygen at 10 minutes ?
  3. Q.29 (b)1 mark
    How does cigarette smoking result in high blood pressure and increase in heart rate ?
  4. Q.29 (c)2 marks
    To which class of compounds does nicotine belong ? Name one other drug from the same class.
  5. India is one of the megadiverse countries housing around 8⋅18{\cdot}1 per cent of global species diversity, although its land area is only 2⋅42{\cdot}4 per cent of the world's land area. Many of the species are highly threatened due to human activities like deforestation, mining and habitat fragmentation. Laws like Wildlife (Protection) Act, 1972 were enacted by the Government of India to preserve our biological wealth. Various conservation measures are being implemented to save the threatened species. The following bar graph shows the number of species conserved under different biodiversity conservation methods. Study the graph and answer the questions.
    Q.30 (a)1 mark
    Which method conserves the highest number of species ? Is it ex situ or in situ conservation ?
  6. Q.30 (b)2 marks
    Which other methods shown in the diagram are opposite to the one identified by you in question (a) ? How are these two conservation approaches different ?
  7. Q.30 (c) (i)1 mark
    Write two features of Biodiversity hotspots.
  8. OR

    Q.30 (c) (ii)1 mark
    To which category do sacred groves belong and how do they help in bio-conservation ?

Section E

5 marks each

  1. Q.31 (a)5 marks
    (i) Describe the series of experiments conducted by Frederick Griffith. Comment on the significance of the result obtained. (ii) State the contribution of Avery, MacLeod and McCarty.
  2. OR

    Q.31 (b)5 marks
    The following questions are based on haemophilia. (i) Work out the crosses between : (I) Normal female and Haemophilic male (II) Carrier female and Normal male (III) Carrier female and Haemophilic male (ii) Write the conclusions you draw from these crosses. Comment on the type of inheritance of the disease. (Use : X – Normal, Xh\text{X}^{\text{h}} – Haemophilic)
  3. Q.32 (a)5 marks
    (i) Explain any two basic principles/core techniques on which biotechnology is based. (ii) Describe any three key tools used in Recombinant DNA technology.
  4. OR

    Q.32 (b)5 marks
    "Early and accurate diagnosis of diseases is vital in medical technology." (i) Name the conventional methods of diagnosis and their disadvantages. (ii) Which three diagnostic techniques have been developed through Biotechnology ? Explain how each one helps in detecting diseases.
  5. Q.33 (a)5 marks
    Oogenesis is a discontinuous process that begins before birth and is completed after puberty. (i) Trace the development of a gamete mother cell till its release from the ovary during ovulation. (ii) Name the two pituitary hormones that play an important role in the process.
  6. OR

    Q.33 (b)5 marks
    (i) Draw a labelled two-celled structure of male gametophyte of an angiosperm. (ii) Name the three layers that surround the cytoplasm of a male gametophyte starting from innermost to outermost layer. (iii) Which organic material makes the outermost layer ? Mention its advantage. (iv) Why is the outermost layer of male gametophyte not continuous ?