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CDS Chemistry · Chemistry in Everyday Life

Antiseptics and the Barium Meal

What tincture of iodine is made of, and why insoluble barium sulphate is safe to swallow for an X-ray while soluble barium salts are poisons.

Why this matters

Three CDS questions, two of them on tincture of iodine (2017 and 2022) and one on the barium meal (2022).

Concept 1 of 2: Tincture of iodine and other antiseptics

An antiseptic kills germs on living tissue, such as a fresh wound. Tincture of iodine is the classic: a little iodine dissolved in alcohol and water, with potassium iodide added so the iodine stays dissolved.

Definition

The facts:

  • Tincture of iodine = a dilute (2–3%) solution of iodine with potassium iodide, in an alcohol–water mixture. It contains no acetone.
  • It is an antiseptic for fresh wounds.
  • Dettol (chloroxylenol and terpineol) and boric acid are other common antiseptics.
  • Antacids (milk of magnesia, sodium hydrogen carbonate) neutralise excess stomach acid.
Component of tincture of iodinePresent?
Iodine (dilute)Yes
Potassium iodideYes — keeps iodine dissolved
Alcohol (ethanol)Yes
WaterYes
AcetoneNoQ
Practice this concept3 quick reps

The same idea in a real exam question:

CDS · 2017 · CDS (II) 2017 — General Knowledge · Q64Moderate

Example 1 · Chemistry in Everyday Life · Medicines and Health Chemistry

Tincture of iodine is an antiseptic for fresh wounds. It is a dilute solution of elemental iodine, which does not contain

No acetone in tincture of iodine

Tincture of iodine is iodine and potassium iodide in alcohol and water. Acetone is not part of it.

The iodine is dilute

Tincture of iodine holds only about 2–3% iodine. Concentrated iodine would burn the skin, so a weak solution is used on wounds.

An antacid is a base

Antacids such as milk of magnesia and sodium hydrogen carbonate are mild bases that neutralise excess stomach acid. They are not acids and not antiseptics.

Antiseptic, not antibiotic

Tincture of iodine is applied to the skin to kill germs on contact. An antibiotic such as penicillin is a medicine taken to fight infection inside the body.

Concept 2 of 2: The barium meal

Barium atoms block X-rays, so a meal containing barium makes the gut show up on an X-ray. Free barium ions are poisonous, though, so the salt must be one that does not dissolve: barium sulphate.

Definition

The facts:

  • Barium sulphate, BaSO₄, is given as a meal before an X-ray of the alimentary canal.
  • It is opaque to X-rays and practically insoluble, so no toxic barium ions are absorbed.
  • Soluble barium salts such as barium chloride are poisonous.
SaltSoluble?Safe as an X-ray meal?
Barium sulphateNoYesQ
Barium chlorideYesNo — poisonous
Practice this concept2 quick reps

The same idea in a real exam question:

CDS · 2022 · CDS (II) 2022 — General Knowledge · Q61Moderate

Example 2 · Chemistry in Everyday Life · Medicines and Health Chemistry

A patient's abdomen (alimentary canal) can be examined by X-ray after administering which one of the following metal salts in the patient's meal ?

Barium sulphate, not barium chloride

The barium meal uses barium sulphate, which does not dissolve. Barium chloride dissolves and is poisonous.

It works because barium blocks X-rays

Barium is heavy and absorbs X-rays, so the coated gut shows white on the film. Strontium sulphate or magnesium chloride would not do this job.

Summary — formulas & gotchas at a glance

A revision cheat-sheet for the formulas and gotchas above. Click any concept name to jump back to its full explanation.

Reference tables (2)

Tincture of iodine and other antiseptics5 rows
Component of tincture of iodinePresent?
Iodine (dilute)Yes
Potassium iodideYes — keeps iodine dissolved
Alcohol (ethanol)Yes
WaterYes
AcetoneNoQ
The barium meal2 rows
SaltSoluble?Safe as an X-ray meal?
Barium sulphateNoYesQ
Barium chlorideYesNo — poisonous

Watch out for (6)

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